trabecular bone diseases

doi: 10.1007/s00198-018-4704-5, 8. doi: 10.1007/s00296-019-04315-7, 21. doi: 10.1016/j.jocd.2017.06.019, 9. Results on Trabecular Bone Score (TBS) in these patients are lacking. “We found a relationship between the [trabecular bone score] and disease activity in patients with AS, but not in those with nonradiographic-axSpA.” Reference Several studies have also recently demonstrated an increased risk of OP in SSc patients, correlated with multiple factors, i.e., low vitamin D levels (1, 5, 13, 15, 27). The lumbar spine TBS score was significantly lower in RA sufferers compared to HS (p < 0.001). Several studies reported a 25% OP prevalence in AS patients and from 10 to 43% radiographic vertebral fractures (17, 18, 47–51). Rheumatology. The TBS values did not differ between RA and HS (p = 0.128), despite lower cumulative and daily GC dose (p < 0.0001). Dickkopf-1 (Dkk-1) serum levels in systemic sclerosis and rheumatoid arthritis patients: correlation with the Trabecular Bone Score (TBS). - Patients affected by rheumatic diseases are prone to an increased risk of low bone mass. Biopsy vs. peripheral computed tomography to assess bone disease in CKD patients on dialysis: differences and similarities. J Bone Miner Res. Lewiecki EM. Front Pharmacol. and Ruaro et al. Bultink IEM. Keywords: trabecular bone score, chronic kidney diseases, fracture prediction, bone microarchitecture, bone and bones Introduction The Kidney Disease Improving Global Outcome (KDIGO) defines chronic kidney disease (CKD) as abnormalities of kidney structure or function, present for >3 months, with implications for health ( 1 ). Increased risk of osteoporosis and fracture in women with systemic sclerosis: a comparative study with rheumatoid arthritis. doi: 10.3904/kjim.2020.065, 50. Clin Exp Nephrol. Numerous authors demonstrated the presence of lower serum 25-hydroxy-vitamin D (25(OH)D) levels in SSc patients than in healthy subjects (HS) (5, 13, 27). Nam SW, Sung YK, Kim D, Cho SK, Song Y, Choi YY, et al. Arch Osteoporos. (2020). Tamirou F, Arnaud L, Talarico R, Scirè CA, Alexander T, Amoura Z, et al. The same studies demonstrated that a positive 25(OH)D value correlated with TBS but not with BMD, as also observed by Koumakis et al. 43. (2020) 23:543–8. Curr Allergy Asthma Rep. (2015) 15:489. doi: 10.1007/s11882-014-0489-6, 47. Epub 2019 Jun 25. Some studies reported that the frequency of OP in women with RA ranged from 30 to 50%, depending on the areas assessed by the DXA, this datum was also confirmed in males (43); osteopenia had a prevalence of about 80% (43). There may be a slight male predilection. 2020 Jul 25;21(1):299. doi: 10.1186/s12882-020-01944-0. Use of dual energy X-ray absorptiometry, the trabecular bone score and quantitative computed tomography in the evaluation of chronic kidney disease-mineral and bone disorders. Several factors may lead to adverse effects on bone mass and to an increased risk of fracture in RA patients, i.e., reduced sun exposure leading to low serum 25(OH) vitamin D levels, reduced physical activity, proximal muscle atrophy due to a sedentary lifestyle, prolonged use of GC and disease-induced bone mass reduction. Monitoring the microcirculation in the diagnosis and follow-up of systemic sclerosis patients: focus on pulmonary and peripheral vascularmanifestations. doi: 10.1080/13102818.2015.1057525, 51.  |  2020 Mar;42(1):8-17. doi: 10.1590/2175-8239-JBN-2019-0008. PLoS ONE. The altered new bone formation in the vertebral cortical area and the impairment of trabecular bone at the level of the vertebral body increase the risk of both OP and VF. the pathogenic aspects. Moreover, future research agenda should aim at further studies investigating into the role of TBS as an outcome measure in the evaluation of anti-osteoporotic treatment efficacy. The fracture prevalence was similar in the RA and SSc groups (29.2 vs. 33.3%, respectively, p = 0.682). Both cortical and trabecular vBMD are reduced at the proximal femur in ACRO patients, regardless of gender, gonadal status, and disease activity. Potential benefits of vitamin D for patients with systemic lupus erythematosus. Two recent studies have reported that the 25(OH)D level is significantly lower in the “Late” than in the “Active” or “Early” capillaroscopy pattern patients (p = 0.002), probably attributable to a reduced vitamin D intestinal absorption (5, 13, 27). (2017) 84:463–6. (2018) 4:e000793. (2018) 6:137–42. These data suggest that TBS reflected trabecular microarchitecture and cortical width measured by bone biopsy in CKD patients. Despite this, to date, there are no guidelines on how to apply it to standard practice, even if the World Health Organization (WHO) established operational definitions of osteoporosis (OP) and osteopenia in postmenopausal Caucasian women (4, 5, 7, 8). Accordingly, previously-published studies have demonstrated large discrepancies in the reported incidence of osteoporosis, based on measurement of bone mineral density (BMD), in patients with AS ranging from 18.7% to 62%. Furthermore, these bone alterations and ligament ossification modify the BMD data and falsely increase lumbar spine BMD values (41, 47, 51). Salman-Monte TC, Torrente-Segarra V, Vega-Vidal AL, Corzo P, Castro-Dominguez F, Ojeda F, et al. |, Creative Commons Attribution License (CC BY).  |  The secondary end-point was to evaluate bone involvement in patients treated with classic (c-DMARD) or biological (b-DMARD) disease-modifying antirheumatic drug therapies and the effect of the duration of the disease and corticosteroid therapy on 3D parameters. Kim et al. NLM Systemic sclerosis: state of the art on clinical practice guidelines. The disturbed bone remodeling cycle present on chronic kidney disease-mineral bone disorders (CKD-MBD) impairs bone turnover and mineralization, leading to reduced bone mass and quality . The preferential loss of trabecular bone, which is more metabolically active and has a higher turnover rate , was previously described in patients with IBD , as well as in patients with anorexia nervosa . Boyadzhieva V, Custodio MR, Sanders-Pinheiro H. J Bras Nefrol transiliac bone with. 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